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intratubular germ cell neoplasia : ウィキペディア英語版
intratubular germ cell neoplasia

Intratubular germ cell neoplasia, abbreviated ITGCN or IGCN and also known as testicular intratubular germ cell neoplasia and intratubular germ cell neoplasia of the testis, is considered a precursor lesion for many types of testicular germ cell tumors.
The common, unspecified variant of the entity was once considered to be a carcinoma in situ〔,〕 although the term "carcinoma ''in situ''" is no longer preferred for ITGCN, unspecified type (ITGCNU) lesions because they are not epithelial lesions.〔Mills, S (ed.) 2009.Sternberg's Diagnostic Pathology. 5th Edition. ISBN 978-0-7817-7942-5〕
The entity will be known as germ cell neoplasia ''in situ'' (GCNIS) in the next WHO classification which is likely to be published in 2016.
==Classification==
The World Health Organisation classification of testicular tumours〔Eble J.N., Sauter G., Epstein J.I., Sesterhenn I.A. (Eds.): World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System
and Male Genital Organs. IARC Press: Lyon 2004. ISBN 92-832-2412-4〕 subdivides ITGCN into (1) a more common, unspecified type (ITGCNU), and (2) other specific subtypes. The most common specific subtypes are intratubular embryonal carcinoma and intratubular seminoma.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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